Understanding how spinal cord injuries affect immune cell movement from bone marrow
Official title: Investigating the role of CSF flow in regulating CNS-adjacent bone marrow-derived myeloid cell egress after spinal cord injury
Funded at Washington University · NIH-10947702 · Data updated 2026-11-12
This study is looking at how the flow of fluid in your spine affects the movement of immune cells after a spinal cord injury, with the hope of finding ways to help you heal better and recover more fully.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $85,864 |
| NIH project number | 1F32NS139284-01 |
| Project ID | NIH-10947702 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a spinal cord injury and are seeking potential new treatments for their condition.
✕Less likely to help
Patients with spinal cord injuries that are chronic and have not shown any signs of recovery may not benefit from this research.
What this research studies
This research investigates the role of cerebrospinal fluid (CSF) flow in regulating the movement of immune cells from the bone marrow to the central nervous system (CNS) after a spinal cord injury. By examining the interactions between the CNS and the immune system, the study aims to uncover how these processes contribute to recovery or further damage following injury. Patients with spinal cord injuries may benefit from insights gained into how immune responses can be modulated to improve healing and functional recovery.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that enhance recovery from spinal cord injuries by targeting immune cell behavior.
How similar studies have gone: Previous research has shown promising results in understanding immune responses in spinal cord injuries, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Plog, Benjamin Arthur — Washington University
- Study coordinator: Plog, Benjamin Arthur
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.