Understanding how spinal cord and dorsal root ganglion stimulation relieve pain
Defining Mechanisms of Pain Relief Associated with Dorsal Root Ganglion and Spinal Cord Stimulation
This study is looking into how spinal cord and dorsal root ganglion stimulators help relieve chronic pain by testing different ways these devices work to block pain signals in the nervous system, which could lead to better treatments for people suffering from long-term pain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10519404 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind pain relief provided by spinal cord and dorsal root ganglion stimulators, which are devices approved for treating chronic pain. The study aims to explore how these devices work by examining different stimulation methods and their effects on pain signals in the nervous system. By conducting a series of experiments, the researchers will test two main theories about how stimulation can block pain signals from reaching the brain. This research could lead to a better understanding of these devices and potentially improve their use in treating chronic pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic pain who have not found relief through conventional treatments.
Not a fit: Patients with acute pain conditions or those who have already responded well to existing pain management therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain management strategies for patients suffering from chronic pain.
How similar studies have performed: Previous research has shown promising results with neuromodulatory devices, indicating that this approach has potential for success.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Koerber, H Richard — University of Pittsburgh at Pittsburgh
- Study coordinator: Koerber, H Richard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.