Understanding how spinal circuits help coordinate movement during walking
Spinal circuits for sensorimotor integration and interlimb coordination during locomotion
This study is looking at how the spinal cord helps us walk steadily and recover from injuries by understanding how it processes signals from our limbs, which could lead to better rehabilitation for people with movement challenges or older adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10878991 on NIH RePORTER |
What this research studies
This research investigates how the spinal cord processes sensory feedback from the limbs to enable stable walking and recovery after spinal cord injuries. By using advanced techniques such as mouse genetics, in vivo electrophysiology, and computational modeling, the study aims to uncover the interactions between sensory signals and spinal circuits that control movement. The goal is to better understand how these mechanisms work together to maintain balance and coordination, especially in individuals with motor disorders or the elderly. This knowledge could lead to improved rehabilitation strategies for those affected by such conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals recovering from spinal cord injuries, those with motor disorders, and elderly patients experiencing balance and coordination issues.
Not a fit: Patients with non-motor related conditions or those not experiencing any mobility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to enhanced rehabilitation techniques for individuals with spinal cord injuries or motor disorders, improving their mobility and quality of life.
How similar studies have performed: Previous research has shown promise in understanding spinal cord circuitry and its role in movement, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Danner, Simon Michael — Drexel University
- Study coordinator: Danner, Simon Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.