Understanding how spinal circuits control coordinated movement
Characterization of spinal circuits underlying motor synergy function
['FUNDING_R01'] · SALK INSTITUTE FOR BIOLOGICAL STUDIES · NIH-10909167
This study is looking at how the nerves in your spine help your muscles work together smoothly, which could lead to better treatments for movement disorders.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SALK INSTITUTE FOR BIOLOGICAL STUDIES (nih funded) |
| Locations | 1 site (La Jolla, UNITED STATES) |
| Trial ID | NIH-10909167 on ClinicalTrials.gov |
What this research studies
This research investigates the spinal circuits that enable the coordination of muscle groups for smooth motor functions. By examining the cellular organization and connectivity of these circuits, the study aims to identify the specific types of neurons involved and the factors that influence their formation. Using advanced techniques like optogenetics and neuronal tracing, researchers will explore how these circuits work together to facilitate complex movements. Patients may benefit from insights gained into motor control, which could inform treatments for movement disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing motor coordination challenges or related neurological conditions.
Not a fit: Patients with purely cognitive or non-motor related neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for patients with motor control issues.
How similar studies have performed: Other research has shown success in understanding motor circuits in various animal models, suggesting that this approach is promising.
Where this research is happening
La Jolla, UNITED STATES
- SALK INSTITUTE FOR BIOLOGICAL STUDIES — La Jolla, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PFAFF, SAMUEL L. — SALK INSTITUTE FOR BIOLOGICAL STUDIES
- Study coordinator: PFAFF, SAMUEL L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.