Understanding how spinal circuits change to improve movement after spinal cord injury.
Crucial spinal circuit changes that mediate locomotion benefits of combined biological/bionic/rehabilitation therapies after spinal cord injury.
This study is looking at how different treatments, like medicine, robotic devices, and physical therapy, can work together to help people recover better after a spinal cord injury, using animal models to see how these therapies can improve movement and mobility.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10447027 on NIH RePORTER |
What this research studies
This research investigates how specific spinal circuits adapt and respond to combined therapies, including biological treatments, bionic devices, and rehabilitation, after a spinal cord injury. By using animal models, the researchers aim to explore the effects of these therapies on spinal plasticity and functionality. The study focuses on the integration of molecular genetics and spinal circuit behavior to enhance recovery outcomes for patients with spinal cord injuries. The goal is to identify effective treatment combinations that can lead to improved locomotion and overall mobility.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a spinal cord injury and are seeking innovative rehabilitation options.
Not a fit: Patients with incomplete spinal cord injuries or those who do not respond to conventional rehabilitation therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant improvements in movement and quality of life for patients with spinal cord injuries.
How similar studies have performed: Previous research has shown promising results with similar approaches, particularly in animal models, indicating potential for success in human applications.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Giszter, Simon F — Drexel University
- Study coordinator: Giszter, Simon F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.