Understanding how sperm-producing cells develop in males
Mechanisms of stem cell specification in the male germline
['FUNDING_R01'] · WASHINGTON STATE UNIVERSITY · NIH-10643841
This study is looking at how sperm-producing cells develop in males, which is important for fertility, and aims to help us understand male reproductive health better, potentially leading to new treatments for infertility.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON STATE UNIVERSITY (nih funded) |
| Locations | 1 site (PULLMAN, UNITED STATES) |
| Trial ID | NIH-10643841 on ClinicalTrials.gov |
What this research studies
This research investigates the early developmental processes that lead to the formation of sperm-producing cells in males, which are essential for male fertility. By studying specific genes and using advanced mouse models, the researchers aim to uncover the mechanisms that trigger the formation of spermatogonial stem cells, which are crucial for continuous sperm production. The findings could provide insights into male infertility and potential therapeutic approaches. Patients may benefit from a better understanding of male reproductive health and fertility treatments.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are adult males experiencing infertility issues.
Not a fit: Patients who are not male or those who do not have concerns related to male fertility may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for male infertility and enhance our understanding of male reproductive health.
How similar studies have performed: While the specific mechanisms being studied are not fully understood, similar research has shown promise in advancing knowledge about male fertility and spermatogenesis.
Where this research is happening
PULLMAN, UNITED STATES
- WASHINGTON STATE UNIVERSITY — PULLMAN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OATLEY, JON M — WASHINGTON STATE UNIVERSITY
- Study coordinator: OATLEY, JON M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.