Understanding how speech changes in Parkinson's disease

Comprehensive assessment of speech physiology and acoustics in Parkinson's disease progression

['FUNDING_R01'] · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · NIH-11010337

This study looks at how the way you speak changes with Parkinson's disease and how that affects your communication experience, so we can find out what really matters to you and help doctors choose the best treatments.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBOSTON UNIVERSITY (CHARLES RIVER CAMPUS) (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11010337 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between speech physiology and patient-centered outcomes in individuals with Parkinson's disease. By examining how changes in speech mechanisms affect communication quality, the study aims to identify which physiological aspects are most relevant to patients' experiences. The approach includes a comprehensive, longitudinal analysis of speech, physiology, and acoustics in a large sample of participants, allowing for a better understanding of the factors that influence speech intelligibility and naturalness. The findings could help clinicians prioritize effective therapies based on what matters most to patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience speech difficulties.

Not a fit: Patients with Parkinson's disease who do not have speech problems may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved speech therapy strategies that enhance communication quality for individuals with Parkinson's disease.

How similar studies have performed: Previous research has shown promising results in understanding speech changes in neurological conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.