Understanding how specific tissues develop and shape the body in embryos
Molecular drivers of tissue-specific morphogenetic programs
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-11060945
This study is looking at how certain birth defects, like problems with the spine and brain, happen in developing embryos by using zebrafish to learn how different parts of the body grow together, which could help us find ways to prevent these issues in the future.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11060945 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind the development of congenital malformations, particularly focusing on neural tube defects in embryos. By studying zebrafish, which serve as a model organism, the research aims to uncover how different tissues coordinate their growth and behavior during early development. The approach involves examining the cellular processes that lead to the proper formation of the neural tube, which is crucial for the healthy development of the nervous system. Insights gained from this research could help identify the causes of birth defects and improve prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are expectant parents, particularly those with a family history of congenital malformations or neural tube defects.
Not a fit: Patients who are adults or those without a history of congenital malformations may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of birth defects, ultimately improving health outcomes for children.
How similar studies have performed: Previous research has shown success in using model organisms like zebrafish to study developmental processes, indicating that this approach is promising.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILLIAMS, MARGOT L.K. — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: WILLIAMS, MARGOT L.K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.