Understanding how specific spinal neurons help regain posture after spinal cord injury
Official title: The role of propriospinal neurons in the recovery of posture after spinal cord injury
Funded at Northwestern University at Chicago · NIH-11060986 · Data updated 2026-11-12
This study is looking at how certain nerve cells in the spinal cord can help people stand and balance better after a spinal cord injury, with the hope of finding new ways to improve movement and daily activities for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $484,533 |
| NIH project number | 5R01NS132487-02 |
| Project ID | NIH-11060986 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced a spinal cord injury.
✕Less likely to help
Patients with spinal cord injuries who are not able to participate in the research due to age or other health conditions may not benefit from this research.
What this research studies
This research investigates the role of propriospinal neurons in restoring the ability to maintain posture following spinal cord injury. By studying these neurons in animal models, the research aims to uncover how they contribute to standing and balance, which are critical for mobility and daily activities. The approach involves recording the activity of these neurons in decerebrate animals to understand their function and potential for rehabilitation. The findings could lead to new strategies for improving postural control in individuals with spinal cord injuries.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that enhance postural stability and mobility for patients with spinal cord injuries.
How similar studies have gone: Previous research has shown promise in understanding spinal cord circuits, but the specific focus on propriospinal neurons for posture recovery is a novel approach.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Heckman, Charles — Northwestern University at Chicago
- Study coordinator: Heckman, Charles
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.