Understanding how specific spinal neurons affect movement after spinal cord injury
Propriopsinal neuron function in normal and post-SCI locomotion
This study is looking at how certain nerve cells in the spinal cord help control movement, especially after someone has a spinal cord injury, to find better ways to help people recover their ability to walk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project ID | NIH-10816395 on NIH RePORTER |
What this research studies
This research investigates the role of propriospinal neurons in controlling locomotion, particularly after spinal cord injuries (SCI). By using advanced molecular tools to manipulate these neurons and sophisticated gait analysis techniques, the researchers aim to understand how these neurons contribute to movement patterns. The study will focus on two types of spinal interneurons and their interactions in both healthy and injured spinal cords, providing insights that could lead to improved rehabilitation strategies for patients with SCI.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who have experienced a spinal cord injury and are seeking ways to improve their locomotion.
Not a fit: Patients with complete spinal cord injuries or those who are not within the age range of 21 years and older may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance recovery of movement in individuals with spinal cord injuries.
How similar studies have performed: Previous research has shown promise in understanding spinal cord circuitry and its role in locomotion, suggesting that this approach could yield valuable insights.
Where this research is happening
Louisville, United States
- University of Louisville — Louisville, United States (Active)
Researchers
- Principal investigator: Magnuson, David Sk — University of Louisville
- Study coordinator: Magnuson, David Sk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.