Understanding how specific retinal cells process visual information
Official title: Characterizing the Unique Biophysical Properties of the CBC2 OFF Cone Bipolar Cell
Funded at Oregon Health & Science University · NIH-10995988 · Data updated 2026-11-12
This study is looking at a special type of retinal cell that helps us see, to learn how it works and communicates with other cells in the eye, which could help us understand vision better and find new ways to treat eye problems.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $74,284 |
| NIH project number | 1F32EY035907-01A1 |
| Project ID | NIH-10995988 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing visual processing disorders or those with specific retinal conditions.
✕Less likely to help
Patients with conditions unrelated to retinal function or those who do not have visual processing issues may not benefit from this research.
What this research studies
This research investigates the unique properties of a specific type of retinal cell known as the CBC2 OFF cone bipolar cell, which plays a crucial role in how we perceive visual information. The study aims to uncover the mechanisms by which these cells process signals from photoreceptors and communicate with other retinal cells. Using advanced techniques like electrophysiology and super-resolution microscopy, researchers will explore how these cells contribute to visual processing and their interactions with other cell types in the retina. This could lead to a better understanding of visual function and potential implications for treating visual disorders.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of retinal function and lead to new treatments for visual impairments.
How similar studies have gone: Other research has shown promise in understanding retinal cell functions, but this specific focus on CBC2 cells is relatively novel.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Wakeham, Colin M — Oregon Health & Science University
- Study coordinator: Wakeham, Colin M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.