Understanding how specific retinal cells process visual information

Characterizing the Unique Biophysical Properties of the CBC2 OFF Cone Bipolar Cell

['FUNDING_FELLOWSHIP'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10995988

This study is looking at a special type of retinal cell that helps us see, to learn how it works and communicates with other cells in the eye, which could help us understand vision better and find new ways to treat eye problems.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-10995988 on ClinicalTrials.gov

What this research studies

This research investigates the unique properties of a specific type of retinal cell known as the CBC2 OFF cone bipolar cell, which plays a crucial role in how we perceive visual information. The study aims to uncover the mechanisms by which these cells process signals from photoreceptors and communicate with other retinal cells. Using advanced techniques like electrophysiology and super-resolution microscopy, researchers will explore how these cells contribute to visual processing and their interactions with other cell types in the retina. This could lead to a better understanding of visual function and potential implications for treating visual disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing visual processing disorders or those with specific retinal conditions.

Not a fit: Patients with conditions unrelated to retinal function or those who do not have visual processing issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of retinal function and lead to new treatments for visual impairments.

How similar studies have performed: Other research has shown promise in understanding retinal cell functions, but this specific focus on CBC2 cells is relatively novel.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.