Understanding how specific proteins influence human cell development
Defining the role of ILF2-ILF3 in human cell fate
This study is looking at how certain proteins help shape the way our cells grow and change during pregnancy, which could help us understand birth defects better and find new ways to treat them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10997240 on NIH RePORTER |
What this research studies
This research investigates the role of ILF2-ILF3 proteins in determining how human cells develop and differentiate during fetal growth. By examining the interactions between DNA and RNA regulation, the study aims to uncover how these proteins influence the fate of embryonic cells. The approach involves manipulating the expression of ILF2-ILF3 to observe its effects on cell identity and development. This could lead to new insights into congenital malformations and potential therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are expectant parents concerned about congenital malformations or those with a family history of developmental disorders.
Not a fit: Patients who are not pregnant or do not have a history of congenital malformations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for congenital malformations that arise during fetal development.
How similar studies have performed: Other research has shown promising results in understanding gene regulation in cell differentiation, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Park, Emily J — Baylor College of Medicine
- Study coordinator: Park, Emily J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.