Understanding how specific proteins affect the formation of cilia in lung cells
Official title: Elucidating the Roles of the Membrane-Binding Proteins ciBAR1 and ciBAR2 in Ciliogenesis
Funded at State University New York Stony Brook · NIH-10899487 · Data updated 2026-11-12
This study is looking at how two specific proteins help in the growth of tiny hair-like structures in the lungs that keep them clear of mucus and germs, which could help us understand more about lung diseases that happen when these structures don’t work properly.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | August 23, 2023 |
| Project end | August 22, 2026 |
| Funding year | 2024 |
| Award (this year) | $41,340 |
| NIH project number | 5F31HL168828-02 |
| Project ID | NIH-10899487 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with chronic pulmonary diseases or genetic conditions affecting ciliary function.
✕Less likely to help
Patients without chronic lung conditions or genetic predispositions related to ciliary dysfunction may not benefit from this research.
What this research studies
This research investigates the roles of two membrane-binding proteins, ciBAR1 and ciBAR2, in the development of cilia, which are essential for clearing mucus and pathogens from the lungs. By using innovative knockout mouse models, the study aims to uncover how these proteins contribute to ciliary function and the differentiation of airway ciliated cells. The findings could provide insights into the mechanisms behind chronic lung diseases and ciliopathies, which are often linked to impaired ciliary function.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for patients suffering from chronic lung diseases and ciliopathies.
How similar studies have gone: Previous research has shown promising results in understanding ciliary function and its implications for lung health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Kim, Eunice Na Young — State University New York Stony Brook
- Study coordinator: Kim, Eunice Na Young
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.