Understanding how specific proteins affect plant growth and development

Structural and Functional Analysis of Nucleocytoplasmic Protein O-Glycosyltransferases in Plants

NIH-funded research Duke University · NIH-11098225

This study is looking at how two proteins, SPINDLY and SECRET AGENT, help plants like Arabidopsis grow and respond to their environment by changing other proteins, which could help us understand how plants adapt to different conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11098225 on NIH RePORTER

What this research studies

This research investigates the roles of two important proteins, SPINDLY and SECRET AGENT, in the process of protein glycosylation in plants, specifically in Arabidopsis. By examining how these proteins modify transcription regulators, the research aims to uncover the molecular mechanisms that control plant growth and responses to environmental changes. The approach includes detailed structural and functional analyses of these proteins and their interactions with other cellular components. This could lead to insights into how plants adapt and develop under varying conditions.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be agricultural scientists and plant biologists interested in crop development and genetic engineering.

Not a fit: Patients with no interest or involvement in plant biology or agriculture may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of plant growth regulation, potentially leading to improved agricultural practices and crop yields.

How similar studies have performed: While the specific focus on these glycosyltransferases may be novel, similar research in plant signaling and development has shown promising results in understanding plant biology.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.