Understanding how specific potassium channels work in cells
Investigation of the Role of the KCNH Voltage-Gated Potassium Channel Intracellular Domains in Gating
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10899787
This study is looking at special channels in our cells that help control electrical signals, which could help us understand how problems with these channels might affect health and lead to new treatments for related conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10899787 on ClinicalTrials.gov |
What this research studies
This research investigates the KCNH voltage-gated potassium channels, focusing on their intracellular domains and how these regions influence the channel's gating mechanisms. By examining the molecular structure and function of these channels, the research aims to uncover critical insights into their role in cellular activity. Patients may benefit from a deeper understanding of how these channels affect various physiological processes, potentially leading to new therapeutic strategies for conditions related to potassium channel dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit would include individuals with conditions linked to potassium channel dysfunction.
Not a fit: Patients with unrelated health issues or those not affected by potassium channel disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions associated with potassium channel abnormalities.
How similar studies have performed: While the specific focus on KCNH channels may be novel, research on voltage-gated potassium channels has shown promise in understanding various cardiac and neurological conditions.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STEVENS-SOSTRE, WHITNEY ALEXANDRA — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: STEVENS-SOSTRE, WHITNEY ALEXANDRA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.