Understanding how specific nerve cells contribute to migraine and facial pain.
The Penn Human Precision Pain Center (HPPC): Discovery and Functional Evaluation of Human Primary Somatosensory Neuron Types at Normal and Chronic Pain Conditions
This study is looking at the nerve cells that play a role in migraines and facial pain to find new ways to help people who suffer from these headaches.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10806545 on NIH RePORTER |
What this research studies
This research focuses on the complex neurological disorder of migraine, which affects many individuals and is linked to changes in nerve sensations in the face and head. The Penn Human Precision Pain Center aims to investigate the molecular and cellular characteristics of sensory neurons involved in migraine and facial pain by analyzing human tissue samples. The research will involve a multidisciplinary team and utilize advanced techniques to gather detailed information about these nerve cells under normal and migraine conditions. By understanding these mechanisms, the research seeks to identify potential new treatment targets for migraine sufferers.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who experience chronic migraines or facial pain.
Not a fit: Patients with acute pain conditions unrelated to migraines or facial pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for migraine and related facial pain conditions.
How similar studies have performed: Previous research has shown promise in understanding pain mechanisms through similar approaches, indicating potential for success in this area.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Luo, Wenqin — University of Pennsylvania
- Study coordinator: Luo, Wenqin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.