Understanding how specific immune cells affect breast tissue health and development
Functions of ductal- and stromal-associated macrophages in the mammary gland
This study is looking at how certain immune cells in the breast help keep breast tissue healthy and develop properly, which could lead to new insights about breast health for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-10885118 on NIH RePORTER |
What this research studies
This research investigates the roles of different types of immune cells, specifically macrophages, in the mammary gland. It aims to understand how these cells contribute to the health and development of breast tissue by examining their functions and the factors they produce. The study uses advanced techniques to analyze the behavior of these immune cells during various stages of mammary gland development, particularly focusing on how they maintain tissue balance and respond to changes. By identifying key molecules involved in these processes, the research seeks to uncover new insights into breast health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of breast cancer or those interested in understanding breast health.
Not a fit: Patients who are not affected by breast tissue conditions or those outside the age range of 21+ years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating breast diseases, including breast cancer.
How similar studies have performed: Previous research has shown promising results in understanding immune cell functions in other tissues, suggesting potential for success in this area as well.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Machado, Heather L — Tulane University of Louisiana
- Study coordinator: Machado, Heather L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.