Understanding how specific gene fusions contribute to blood cancers
Elucidating the molecular mechanism of Daple- FLT3 and Daple-PDGFRB gene fusion in blood cancers
This study is looking at how certain gene fusions related to blood cancers work, with the hope that understanding them better will help create more effective treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State Poly U Pomona NIH-funded |
| Lab location | 1 site (Pomona, United States) |
| Project ID | NIH-11037219 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms behind the Daple-FLT3 and Daple-PDGFRB gene fusions, which are linked to various blood cancers. By analyzing these gene fusions, the research aims to uncover how they influence cancer development and progression. Patients may benefit from insights that could lead to targeted therapies or improved treatment strategies for hematopoietic malignancies. The approach involves advanced molecular biology techniques to study the interactions and effects of these gene fusions in cancer cells.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with hematopoietic malignancies, particularly those with known Daple-FLT3 or Daple-PDGFRB gene fusions.
Not a fit: Patients with blood cancers that do not involve the Daple-FLT3 or Daple-PDGFRB gene fusions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies for patients with specific blood cancers caused by these gene fusions.
How similar studies have performed: Previous research has shown promising results in understanding gene fusions in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Pomona, United States
- California State Poly U Pomona — Pomona, United States (Active)
Researchers
- Principal investigator: Ear, Jason — California State Poly U Pomona
- Study coordinator: Ear, Jason
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.