Understanding how specific cells respond to COVID-19 and its long-term effects
Official title: Cell Derivation and Maintenance Core
Funded at Ohio State University · NIH-11072970 · Data updated 2026-11-12
This study is looking at how COVID-19 affects the body over time, especially the ongoing symptoms known as Long-COVID, and it's for anyone interested in understanding how we can better treat these lasting effects by examining different types of cells from people who have had the virus.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | April 10, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $429,217 |
| NIH project number | 5P01AI175399-02 |
| Project ID | NIH-11072970 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced COVID-19, particularly those with persistent symptoms.
✕Less likely to help
Patients who have not been infected with COVID-19 or do not exhibit any long-term symptoms may not benefit from this research.
What this research studies
This research focuses on the impact of COVID-19, particularly the long-term symptoms known as Long-COVID. It aims to identify the specific cell types and pathways involved in controlling inflammation and the virus's virulence. The study will utilize primary human and mouse airway epithelial cells, immune cells, and brain cells, as well as blood samples from both infected and non-infected patients. By analyzing these cells, the research seeks to uncover new therapeutic targets for treating COVID-19 and its lingering effects.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for patients suffering from Long-COVID and improve overall understanding of the disease.
How similar studies have gone: Other research has shown promise in understanding COVID-19 through similar cellular approaches, indicating potential for success in this area.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Cormet-Boyaka, Estelle a — Ohio State University
- Study coordinator: Cormet-Boyaka, Estelle a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.