Understanding how specific cells in the retina process visual signals

Functional properties of amacrine cells in the mammalian retina

NIH-funded research University of California Berkeley · NIH-11063173

This study is looking at special cells in the eye called amacrine cells to understand how they help us see by processing visual information, which could lead to better treatments for vision problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Berkeley NIH-funded
Lab location1 site (Berkeley, United States)
Project IDNIH-11063173 on NIH RePORTER

What this research studies

This research investigates the functional roles of amacrine cells in the mammalian retina, which are crucial for visual signal processing. Using advanced techniques like electrophysiological recordings, the study will analyze how these cells interact with other retinal cells to influence visual perception. The research will focus on genetically labeled amacrine cells and their synaptic mechanisms, aiming to uncover how they contribute to the processing of visual information under different light conditions. Patients may benefit from insights gained into retinal function and potential treatments for vision-related disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with retinal disorders or those at risk of vision loss.

Not a fit: Patients with non-retinal related vision issues or those who do not have any retinal cell dysfunction may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for treating blindness and other visual impairments.

How similar studies have performed: Other research has shown success in understanding retinal cell functions, but this specific investigation into amacrine cells is relatively novel.

Where this research is happening

Berkeley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.