Understanding how specific brain regions affect social behavior in mice
Official title: Neuroanatomy and function of the ventral claustrum-dorsal endopiriform nucleus in mice
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11048246 · Data updated 2026-11-12
This study is looking at how a specific part of the brain helps mice understand and respond to social situations, which could help us learn more about social behavior in people with conditions like Alzheimer's and autism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | January 24, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $525,912 |
| NIH project number | 1R01NS136371-01A1 |
| Project ID | NIH-11048246 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals diagnosed with neurodevelopmental disorders, neurological disorders, or neurodegenerative diseases, particularly those affecting social behavior.
✕Less likely to help
Patients with conditions unrelated to social behavior dysfunction or those under 21 years old may not receive benefit from this research.
What this research studies
This research investigates the role of the ventral claustrum-dorsal endopiriform nucleus in regulating social behavior by examining how it processes emotions and integrates sensory information. Using advanced techniques, the study will analyze the neural activity of specific neurons in this brain region during various social interactions in mice. The findings aim to uncover the neurobiological mechanisms that contribute to social behavior, particularly in the context of disorders like Alzheimer's disease and autism.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the treatment of social behavior dysfunctions associated with neurodevelopmental and neurodegenerative disorders.
How similar studies have gone: Previous studies have shown promising results in understanding the neural mechanisms of social behavior, suggesting that this research could build on established findings.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Kim, Yongsoo — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Kim, Yongsoo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.