Understanding how specific brain regions affect social behavior in mice

Neuroanatomy and function of the ventral claustrum-dorsal endopiriform nucleus in mice

NIH-funded research Pennsylvania State Univ Hershey Med Ctr · NIH-11048246

This study is looking at how a specific part of the brain helps mice understand and respond to social situations, which could help us learn more about social behavior in people with conditions like Alzheimer's and autism.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State Univ Hershey Med Ctr NIH-funded
Lab location1 site (Hershey, United States)
Project IDNIH-11048246 on NIH RePORTER

What this research studies

This research investigates the role of the ventral claustrum-dorsal endopiriform nucleus in regulating social behavior by examining how it processes emotions and integrates sensory information. Using advanced techniques, the study will analyze the neural activity of specific neurons in this brain region during various social interactions in mice. The findings aim to uncover the neurobiological mechanisms that contribute to social behavior, particularly in the context of disorders like Alzheimer's disease and autism.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals diagnosed with neurodevelopmental disorders, neurological disorders, or neurodegenerative diseases, particularly those affecting social behavior.

Not a fit: Patients with conditions unrelated to social behavior dysfunction or those under 21 years old may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new insights into the treatment of social behavior dysfunctions associated with neurodevelopmental and neurodegenerative disorders.

How similar studies have performed: Previous studies have shown promising results in understanding the neural mechanisms of social behavior, suggesting that this research could build on established findings.

Where this research is happening

Hershey, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.