Understanding how specific brain pathways affect mood and addiction.

Connectivity and Function of the Asymmetric Habenulo-Interpeduncular Pathway

NIH-funded research Dartmouth College · NIH-10983298

This study is looking at a specific part of the brain that affects sleep, anxiety, and addiction to better understand how it works when we face negative experiences, which could help find new ways to treat mood disorders and addiction.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionDartmouth College NIH-funded
Lab location1 site (Hanover, United States)
Project IDNIH-10983298 on NIH RePORTER

What this research studies

This research investigates the habenulo-interpeduncular pathway in the brain, which plays a crucial role in various functions such as sleep, anxiety, and addiction. By using advanced techniques like genetic manipulation and imaging, the study aims to identify different types of neurons in this pathway and how they respond to negative experiences. This could help in understanding the underlying mechanisms of mood disorders and addiction, potentially leading to new treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing mood disorders or addiction-related issues.

Not a fit: Patients with neurological conditions unrelated to mood or addiction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for mood disorders and addiction.

How similar studies have performed: Previous research has shown promising results in understanding brain pathways related to addiction and mood disorders, indicating that this approach has potential for success.

Where this research is happening

Hanover, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorderAffective Disordersautism spectral disorderautism spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.