Understanding how specific brain neurons develop and function
Development and Function of Medulla Tangential Neurons
['FUNDING_R21'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11137444
This study is looking at special brain cells that help shape how our brains develop, especially in relation to conditions like autism, to better understand how these cells work and how problems with them might affect brain health.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11137444 on ClinicalTrials.gov |
What this research studies
This research investigates the role of tangentially projecting neurons in the organization of brain structures, particularly focusing on the medulla visual projection neurons in the developing human cortex. By using advanced genetic analysis in a model organism, the study aims to trace the lineage of these neurons and understand their contributions to brain assembly. The research will explore how defects in these neurons may relate to neurodevelopmental disorders, including autism spectrum disorder. Patients may benefit from insights gained about the underlying mechanisms of brain development and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with autism spectrum disorder or related neurodevelopmental conditions.
Not a fit: Patients with neurodevelopmental disorders not related to the functions of the medulla visual projection neurons may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of neurodevelopmental disorders and lead to new treatment strategies for conditions like autism.
How similar studies have performed: While the specific focus on medulla visual projection neurons is novel, similar approaches in understanding brain development have shown promise in other studies.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TREISMAN, JESSICA E — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: TREISMAN, JESSICA E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder