Understanding how specific brain neurons control sleep
Neuronal Circuit Controlling Sleep-Promoting Ventrolateral Preoptic Neurons
This study is looking at special brain cells that help us sleep, to understand how they work with other brain areas that control when we sleep and wake up, which could help us find better ways to treat sleep problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11012254 on NIH RePORTER |
What this research studies
This research investigates the role of specific neurons in the brain that promote sleep, focusing on the ventrolateral preoptic (VLPOGal) neurons. It aims to uncover how these neurons interact with other brain circuits that regulate sleep and wakefulness. By studying the connections and signals between sleep-promoting and wake-promoting neurons, the research seeks to fill gaps in our understanding of sleep regulation. This could lead to insights into how sleep disorders develop and how they might be treated.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing sleep disorders or aberrant sleep patterns.
Not a fit: Patients with no sleep-related issues or those whose sleep disturbances are caused by non-neurological factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for sleep disorders, improving sleep quality for many patients.
How similar studies have performed: Previous research has shown promising results in understanding sleep regulation through similar approaches, indicating potential for success in this area.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Arrigoni, Elda — Beth Israel Deaconess Medical Center
- Study coordinator: Arrigoni, Elda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.