Understanding how specific brain neurons affect social behavior
Official title: Role of brain Avpr1a-expressing neurons in modulation of social behavior
Funded at Rowan University School/osteopathic Med · NIH-10916475 · Data updated 2026-11-12
This study is looking at how certain brain cells that help control social behavior might affect kids with autism, with the hope of finding new ways to support them in building better social connections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rowan University School/osteopathic Med NIH-funded |
| Lab location | 1 site (Stratford, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $402,500 |
| NIH project number | 5R01MH131807-02 |
| Project ID | NIH-10916475 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who exhibit atypical social behaviors or are diagnosed with autism spectrum disorder.
✕Less likely to help
Patients who are older than 11 years or do not exhibit any social behavior challenges may not benefit from this research.
What this research studies
This research investigates the role of neurons that express the arginine vasopressin receptor in the brain and how they influence social behaviors in children. By examining the neurobiological mechanisms behind social interactions, the study aims to identify potential treatment targets for conditions like autism spectrum disorder (ASD) that disrupt social behavior. The approach includes analyzing the effects of these neurons on both pro-social and anti-social behaviors, which could lead to innovative therapeutic interventions. The research will involve various methodologies, including anatomical studies and behavioral assessments, to gain insights into the neural underpinnings of social behavior.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve social interactions and overall quality of life for individuals with autism and related conditions.
How similar studies have gone: Previous research has shown that understanding the neurobiology of social behavior can lead to significant advancements in treatment approaches, indicating that this area of study has potential for success.
Where this research is happening
-
Rowan University School/osteopathic Med
Stratford, United States Active
Researchers
- Principal investigator: Rood, Benjamin David — Rowan University School/osteopathic Med
- Study coordinator: Rood, Benjamin David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.