Understanding how specific brain neurons affect social behavior
Role of brain Avpr1a-expressing neurons in modulation of social behavior
['FUNDING_R01'] · ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED · NIH-10916475
This study is looking at how certain brain cells that help control social behavior might affect kids with autism, with the hope of finding new ways to support them in building better social connections.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED (nih funded) |
| Locations | 1 site (STRATFORD, UNITED STATES) |
| Trial ID | NIH-10916475 on ClinicalTrials.gov |
What this research studies
This research investigates the role of neurons that express the arginine vasopressin receptor in the brain and how they influence social behaviors in children. By examining the neurobiological mechanisms behind social interactions, the study aims to identify potential treatment targets for conditions like autism spectrum disorder (ASD) that disrupt social behavior. The approach includes analyzing the effects of these neurons on both pro-social and anti-social behaviors, which could lead to innovative therapeutic interventions. The research will involve various methodologies, including anatomical studies and behavioral assessments, to gain insights into the neural underpinnings of social behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who exhibit atypical social behaviors or are diagnosed with autism spectrum disorder.
Not a fit: Patients who are older than 11 years or do not exhibit any social behavior challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve social interactions and overall quality of life for individuals with autism and related conditions.
How similar studies have performed: Previous research has shown that understanding the neurobiology of social behavior can lead to significant advancements in treatment approaches, indicating that this area of study has potential for success.
Where this research is happening
STRATFORD, UNITED STATES
- ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED — STRATFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROOD, BENJAMIN DAVID — ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED
- Study coordinator: ROOD, BENJAMIN DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.