Understanding how specific brain circuits process visual motion in mice
Molecular mechanisms underlying direction-selective circuit assembly and function in the mouse visual system
This study is looking at how certain brain cells in mice work together to help them see and track moving things, which could help us understand more about how our own vision works and what happens when there are problems with it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10887507 on NIH RePORTER |
What this research studies
This research investigates the development of neural circuits in the mouse visual system that are responsible for detecting motion. It focuses on how different types of neurons, including bipolar cells and retinal ganglion cells, are formed and connected to create direction-selective circuits. By examining the molecular mechanisms and gene expression involved in these processes, the research aims to uncover how these circuits function and respond to visual stimuli. This could provide insights into the fundamental workings of the visual system and potential implications for understanding visual processing disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with visual processing disorders or related neurological conditions.
Not a fit: Patients without any visual processing issues or those not affected by neurological conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of visual processing, potentially leading to new treatments for visual disorders.
How similar studies have performed: Other research has shown success in understanding neural circuit development, but this specific investigation into direction-selective circuits is relatively novel.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kolodkin, Alex L — Johns Hopkins University
- Study coordinator: Kolodkin, Alex L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.