Understanding how specific brain circuits influence emotional and social behaviors
Temporal Specification of Basal Forebrain Circuitry
This study is looking at a part of the brain that helps control emotions and social behavior to understand how different types of brain cells work together, especially in relation to anxiety and bipolar disorder, so that we can find better treatments for these conditions.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11074678 on NIH RePORTER |
What this research studies
This research investigates the basal forebrain's septal complex, which plays a crucial role in regulating emotional and social behaviors. By examining the medial and lateral septum regions, the study aims to uncover the genetic and molecular pathways that contribute to the diversity of neuronal cell types and their functions. The research focuses on how these neurons interact with other brain regions to influence anxiety and stress responses, particularly in relation to psychiatric disorders like bipolar disorder and anxiety-related conditions. Patients may benefit from insights into how these circuits can be targeted for therapeutic interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with anxiety disorders, bipolar disorder, or related psychiatric conditions.
Not a fit: Patients with neurological disorders unrelated to emotional or social behavior may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for anxiety and mood disorders by targeting specific brain circuits.
How similar studies have performed: Previous research has shown promising results in understanding brain circuitry related to emotional regulation, suggesting potential for success in this area.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Harwell, Corey C — University of California, San Francisco
- Study coordinator: Harwell, Corey C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.