Understanding how specific brain cells control communication in neuropsychiatric disorders

Evaluating a cell type-specific mechanism of glutamatergic synapse function and organization

NIH-funded research Tufts University Boston · NIH-11162711

This study is looking at how special brain cells called interneurons help manage communication in the brain, which could lead to better treatments for anxiety and autism.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionTufts University Boston NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11162711 on NIH RePORTER

What this research studies

This research investigates the role of a specific type of brain cell, known as interneurons, in regulating communication within the brain. It focuses on how these cells respond to signals from other neurons and how this affects conditions like anxiety and autism. By examining the unique properties of synapses, or connections, between these cells, the research aims to uncover mechanisms that could lead to better treatments for neuropsychiatric disorders. The study employs advanced techniques to analyze the protein composition and organization of these synapses.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with neuropsychiatric disorders, particularly those related to anxiety and autism spectrum disorders.

Not a fit: Patients with neuropsychiatric disorders not related to anxiety or autism may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for treating neuropsychiatric disorders such as anxiety and autism.

How similar studies have performed: Previous research has shown promising results in understanding synaptic function in neuropsychiatric disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions autism spectral disorderautism spectrum disorderAutistic Disorderautistic spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.