Understanding how specific brain cells affect visual processing in primates
Roles of parvalbumin-expressing neurons in primate cortical processing
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF WASHINGTON · NIH-11065108
This study is looking at special brain cells that help control how we see things, and it's for anyone interested in how our brains manage what we pay attention to and how we process visual information.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11065108 on ClinicalTrials.gov |
What this research studies
This research investigates the role of parvalbumin-expressing neurons in the primate brain, particularly how they contribute to gain control in visual processing. By using advanced viral genetic tools, the study aims to determine whether these inhibitory neurons modulate the activity of other neurons in a similar way to what has been observed in mice. This could provide insights into how the brain adjusts sensitivity to visual stimuli without losing important information. The findings may help in understanding the neural basis of attention and other cognitive functions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals with neurological or psychiatric disorders that may involve dysfunction of inhibitory neurons.
Not a fit: Patients with conditions unrelated to the functioning of inhibitory neurons or those who do not have access to the research facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into neurological and psychiatric disorders linked to dysfunctional inhibitory neurons.
How similar studies have performed: While the role of parvalbumin-expressing neurons has been studied in mice, this research represents a novel application of these findings to primates, making it an untested approach in this context.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BUN, LUKE MAR — UNIVERSITY OF WASHINGTON
- Study coordinator: BUN, LUKE MAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.