Understanding how specific B cells help fight viral infections
The Role of Tbet+ B cells in viral reinfection
['FUNDING_R21'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-11119534
This study is looking at a special type of B cell that helps your body fight off viruses, to see how they develop and make antibodies that keep you safe from getting sick again, which could help us understand immune responses better for everyone, including those with autoimmune conditions.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-11119534 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a unique subset of B cells, known as Tbet+ B cells, in the immune response to viral infections. It focuses on how these B cells mature and differentiate to produce antibodies that protect against reinfection. By examining the mechanisms behind their activation and function, the study aims to clarify their contribution to generating effective anti-viral antibodies. This could lead to better understanding of immune responses in both healthy individuals and those with autoimmune conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced viral infections and may be at risk for reinfection, particularly those with autoimmune conditions.
Not a fit: Patients who have not had viral infections or those with unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of immune responses, potentially leading to improved treatments for viral infections and autoimmune diseases.
How similar studies have performed: Previous studies have shown that understanding specific B cell functions can lead to significant advancements in vaccine development and treatment strategies, indicating a promising avenue for this research.
Where this research is happening
Newark, UNITED STATES
- RUTGERS BIOMEDICAL AND HEALTH SCIENCES — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WEINSTEIN, JASON — RUTGERS BIOMEDICAL AND HEALTH SCIENCES
- Study coordinator: WEINSTEIN, JASON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.