Understanding how some people control HIV without ongoing treatment
Official title: Modeling Viral and T Lymphocyte Dynamics
Funded at Triad National Security, LLC · NIH-10742915 · Data updated 2026-11-12
This study is looking into why some people can keep their HIV levels low even after stopping treatment, and it aims to find new ways to help manage HIV better and improve health for everyone living with the virus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Triad National Security, LLC NIH-funded |
| Lab location | 1 site (Los Alamos, UNITED STATES) |
| Project start | December 23, 2019 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $466,632 |
| NIH project number | 5R01OD011095-31 |
| Project ID | NIH-10742915 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals living with HIV who have previously undergone antiretroviral treatment and are interested in understanding their viral control.
✕Less likely to help
Patients who are not living with HIV or those who have not received antiretroviral treatment may not benefit from this research.
What this research studies
This research investigates the mechanisms behind why certain individuals can maintain low levels of HIV after stopping treatment. By analyzing data from previous studies, the team aims to develop models that explain how viral reservoirs are established and maintained in the body. The research will involve collaboration with experimental scientists to gather novel datasets, which will help identify factors that contribute to achieving a functional cure for HIV. This could lead to new strategies for managing HIV infection and improving patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that allow patients to control HIV without the need for continuous medication.
How similar studies have gone: Previous studies have shown promise in identifying mechanisms of HIV control, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Triad National Security, LLC
Los Alamos, United States Active
Researchers
- Principal investigator: Perelson, Alan S — Triad National Security, LLC
- Study coordinator: Perelson, Alan S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.