Understanding how some people become more vulnerable to alcohol addiction.
Predicting addictive vulnerability to alcohol: Initial sensitivity, tolerance, allostasis and self-administration
This study looks at how people react to alcohol and how those reactions might help us understand who is more likely to develop a tolerance or addiction, and it includes both men and women to get a complete picture.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10682461 on NIH RePORTER |
What this research studies
This research investigates the biological and behavioral responses of individuals to alcohol exposure, focusing on how initial reactions can predict future tolerance and addiction. By using a novel system that simulates alcohol exposure in a controlled environment, the study aims to identify the mechanisms that lead to increased vulnerability to addiction. The research will involve both male and female subjects to ensure a comprehensive understanding of these processes. Ultimately, the goal is to uncover factors that contribute to addiction risk, which could inform prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced varying levels of alcohol exposure and may be at risk for developing addiction.
Not a fit: Patients who have not been exposed to alcohol or have no interest in alcohol consumption may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of individuals at risk for alcohol addiction and more effective prevention strategies.
How similar studies have performed: Previous research has shown promising results in understanding addiction mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Ramsay, Douglas S — University of Washington
- Study coordinator: Ramsay, Douglas S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.