Understanding how some older adults resist Alzheimer's disease and related disorders
NEURAL PHENOTYPES OF RESISTANCE AND RESILIENCY TO AD AND ADRD IN THE OLDEST OF THE OLD
This study is looking at what helps older adults, especially those 65 and up, stay sharp and resilient against Alzheimer's and similar conditions, by exploring how their health, lifestyle, and social connections might protect their thinking skills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10909125 on NIH RePORTER |
What this research studies
This research investigates the factors that contribute to resilience against Alzheimer's disease (AD) and related disorders in older adults, particularly those aged 65 and above. It examines a variety of influences, including demographic, social, and health-related factors, as well as lifestyle choices that may protect against cognitive decline. By analyzing data from older adults, the study aims to identify mechanisms that allow some individuals to maintain cognitive function despite the presence of pathological changes associated with AD. The research employs a comprehensive approach, integrating various domains such as health history, lifestyle, and social networks to understand resilience in aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above, particularly those who are cognitively healthy or exhibit resilience against cognitive impairment.
Not a fit: Patients who are younger than 65 or those already diagnosed with advanced Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or delaying cognitive decline in older adults.
How similar studies have performed: Previous research has shown promising results in understanding resilience factors in aging, indicating that this approach has potential for significant findings.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Salat, David H — Washington University
- Study coordinator: Salat, David H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.