Understanding how some older adults maintain cognitive abilities as they age
Biopsychosocial Mechanisms of Successful Aging
This study is looking at why some older adults, aged 60-80, can keep their memory sharp and brain healthy even when they have signs of Alzheimer's, and it aims to find out what helps them age successfully.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11035073 on NIH RePORTER |
What this research studies
This research investigates why certain older adults do not experience the typical cognitive decline associated with aging, even in the presence of Alzheimer's disease biomarkers. By studying individuals aged 60-80 who show resilience in memory performance and brain function, the research aims to identify the biobehavioral mechanisms that contribute to successful aging. The approach includes analyzing brain anatomy, connectivity, and subjective experiences during cognitive tasks to uncover factors that promote healthy aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 60-80 who demonstrate preserved cognitive abilities despite age-related challenges.
Not a fit: Patients who are younger than 60 or those with significant cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing cognitive health and resilience in older adults.
How similar studies have performed: Previous research has shown promising results in understanding resilience in aging, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Dickerson, Bradford C — Massachusetts General Hospital
- Study coordinator: Dickerson, Bradford C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.