Understanding how some children cope with traumatic experiences
Susceptibility and Resilience to Adverse Childhood Experiences: A Role for Perineuronal Nets
This study is looking at why some kids who go through really tough experiences, like violence or accidents, don’t end up with mental health problems, and it’s exploring how certain brain structures might help them cope better, using young rats to learn more about this resilience so we can find new ways to support kids who face trauma.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | West Virginia University NIH-funded |
| Lab location | 1 site (Morgantown, United States) |
| Project ID | NIH-10886732 on NIH RePORTER |
What this research studies
This research investigates why many children who experience severe stress and traumatic events, such as violence or accidents, do not develop psychological issues. It focuses on the role of perineuronal nets in the brain, which may help some children forget or cope with these adverse experiences. By studying young rats, the researchers aim to uncover the mechanisms behind resilience and memory formation related to trauma. The findings could lead to new treatments that enhance resilience in children exposed to trauma.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 who have experienced adverse childhood events.
Not a fit: Patients who have not experienced any traumatic events or those over the age of 11 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for helping children cope with and recover from traumatic experiences.
How similar studies have performed: Other research has shown promise in understanding resilience to trauma, but this specific approach focusing on perineuronal nets is relatively novel.
Where this research is happening
Morgantown, United States
- West Virginia University — Morgantown, United States (Active)
Researchers
- Principal investigator: Schreurs, Bernard G. — West Virginia University
- Study coordinator: Schreurs, Bernard G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.