Understanding how soft tissue sarcomas respond to radiation therapy
Official title: Non-invasive characterization of human soft tissue sarcoma response to radiation therapy
Funded at Stanford University · NIH-10902079 · Data updated 2026-11-12
This study is looking at tumor and blood samples from patients with soft tissue sarcomas to find out why some tumors don’t respond well to radiation therapy, with the goal of making radiation treatment more effective for those patients.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | August 15, 2022 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $262,249 |
| NIH project number | 5K08CA255425-03 |
| Project ID | NIH-10902079 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with soft tissue sarcomas who are undergoing radiation therapy.
✕Less likely to help
Patients with other types of cancers or those not receiving radiation therapy may not benefit from this research.
What this research studies
This research focuses on analyzing human tumor and blood samples from patients with soft tissue sarcomas to identify factors that contribute to radiation resistance. By understanding these mediators, the research aims to enhance the effectiveness of radiation therapy for these patients. The project is led by Dr. Everett Moding at Stanford University, who is working under the mentorship of experts in genomics, tumor immunology, and radiation biology. The approach combines clinical insights with advanced laboratory techniques to develop better treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved radiation therapy outcomes for patients with soft tissue sarcomas.
How similar studies have gone: Previous research has shown promise in using tumor and blood sample analysis to improve cancer treatment outcomes, indicating that this approach has potential for success.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Moding, Everett James — Stanford University
- Study coordinator: Moding, Everett James
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.