Understanding how sodium channels in the heart are regulated
Post-Transcriptional Regulation of Myocardial Sodium Channels
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10660961
This study looks at how certain proteins affect the sodium channels in your heart that help control your heartbeat, with the goal of finding new ways to understand and treat heart rhythm problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10660961 on ClinicalTrials.gov |
What this research studies
This research investigates the role of sodium channels in the heart, which are essential for generating and controlling heartbeats. It focuses on how these channels are affected by various proteins, particularly in the context of heart diseases that can lead to dangerous arrhythmias. By exploring the molecular mechanisms that regulate these channels, the research aims to uncover new insights into heart function and disease. Patients may benefit from a better understanding of how to manage or treat heart rhythm disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have or are at risk for cardiac arrhythmias.
Not a fit: Patients without any history of heart conditions or arrhythmias may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with heart rhythm disorders.
How similar studies have performed: Previous research has shown promising results in understanding sodium channel regulation, indicating potential for significant advancements in this area.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NERBONNE, JEANNE M. — WASHINGTON UNIVERSITY
- Study coordinator: NERBONNE, JEANNE M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.