Understanding how social stress affects alcohol consumption
Molecular Signatures of Social Stress-Induced Escalation of Drinking
['FUNDING_R21'] · LSU HEALTH SCIENCES CENTER · NIH-10843152
This study is looking at how social stress can lead to drinking more alcohol, using mice to understand how stress affects the brain and behavior, which could help find new ways to support people struggling with alcohol use.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LSU HEALTH SCIENCES CENTER (nih funded) |
| Locations | 1 site (NEW ORLEANS, UNITED STATES) |
| Trial ID | NIH-10843152 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between social stress and increased alcohol consumption using a mouse model. By simulating social defeat stress in rodents, the study aims to uncover the neural mechanisms that link stress to heightened drinking behavior. Researchers will analyze the genetic activity of brain cells activated by both social stress and alcohol exposure, providing insights into how these factors interact at a cellular level. The findings could help identify potential targets for interventions in alcohol use disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing high levels of social stress who may be at risk for alcohol use disorders.
Not a fit: Patients who do not experience social stress or have no history of alcohol use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating alcohol use disorders linked to social stress.
How similar studies have performed: Previous research has shown that social stress can influence substance use behaviors, indicating that this approach has potential for meaningful insights.
Where this research is happening
NEW ORLEANS, UNITED STATES
- LSU HEALTH SCIENCES CENTER — NEW ORLEANS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAIYA, RAJANI — LSU HEALTH SCIENCES CENTER
- Study coordinator: MAIYA, RAJANI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.