Understanding how social isolation affects prairie voles

Breaking bonds in prairie voles

NIH-funded research Florida State University · NIH-11001568

This study looks at how being alone or separated from a partner affects prairie voles, which are social animals, to see how it might relate to feelings of anxiety and depression, and it could help us understand how our own social connections influence mental health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFlorida State University NIH-funded
Lab location1 site (Tallahassee, United States)
Project IDNIH-11001568 on NIH RePORTER

What this research studies

This research investigates the effects of social isolation and partner separation on prairie voles, which are known for their social bonding behaviors. By examining how these experiences influence anxiety and depression-like behaviors, the study aims to uncover the role of oxytocin in social attachment and stress responses. The researchers will analyze changes in neurochemical systems and social behaviors in both male and female voles to better understand the biological mechanisms at play. This work could provide insights into how social relationships impact mental health and stress in humans.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing anxiety or depression related to social isolation or relationship issues.

Not a fit: Patients who do not experience social attachment issues or who have other unrelated mental health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of how social connections influence mental health, potentially informing new treatments for anxiety and depression.

How similar studies have performed: Previous research has shown that social bonding and oxytocin play significant roles in emotional well-being, suggesting that this approach has a foundation in established findings.

Where this research is happening

Tallahassee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.