NIH-funded research NIH-funded research

Understanding how social isolation affects health behaviors

Official title: Interdisciplinary Studies for Mechanisms Underlying Social Isolation-Induced Health Critical Behavior Changes

Funded at Texas A&m University · NIH-10893562 · Data updated 2026-11-12

This study is looking at how being alone for a long time, especially during the COVID-19 pandemic, affects our health habits, like sleep and eating, using fruit flies to understand the brain changes that happen with social isolation, which could help us learn more about how our social lives impact our well-being.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTexas A&m University
NIH-funded
Lab location1 site (College Station, United States)
Project startAugust 1, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$375,416
NIH project number5R35GM150832-02
Project IDNIH-10893562 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing behavioral changes due to prolonged social isolation, particularly during or after the COVID-19 pandemic.

Less likely to help

Patients who have not experienced significant social isolation or related behavioral changes may not benefit from this research.

What this research studies

This research investigates the effects of prolonged social isolation on health-critical behaviors, particularly in the context of the COVID-19 pandemic. Using a model organism, Drosophila melanogaster, the study aims to uncover the biological mechanisms that link social isolation to changes in behavior, such as sleep disruption and eating disorders. By examining how the brain processes social isolation over time, researchers hope to identify specific cells and pathways involved in these changes. This approach could lead to new insights into how social environments influence health and well-being.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and interventions for behavioral issues arising from social isolation.

How similar studies have gone: Other research has shown success in understanding behavioral changes due to social isolation, but this specific approach using Drosophila is relatively novel.

Where this research is happening

  • Texas A&m University
    College Station, United States
    Active

Researchers

  • Principal investigator: Li, Wanhe — Texas A&m University
  • Study coordinator: Li, Wanhe

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.