Understanding how social gaze affects communication in the brain

Prefrontal and Amygdalar Mechanisms of Live Social Gaze Interaction

NIH-funded research Yale University · NIH-10892152

This study looks at how looking at each other while talking affects how we communicate and behave, using monkeys to understand how certain parts of the brain help us pay attention to social cues during these interactions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10892152 on NIH RePORTER

What this research studies

This research investigates how live social gaze interactions influence communication and behavior by examining the neural circuits involved in these processes. Using a non-human primate model, the study focuses on the roles of specific brain regions, particularly the orbitofrontal cortex and the basolateral amygdala, in regulating attention to social cues. The researchers aim to establish how these brain areas interact during social gaze exchanges, which are crucial for effective interpersonal communication. By analyzing the differences between live interactions and passive observations, the study seeks to uncover the underlying mechanisms that facilitate social cognition.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing difficulties with social interactions or communication, potentially including those with autism spectrum disorders or social anxiety.

Not a fit: Patients who do not have any social interaction difficulties or cognitive impairments may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of social communication disorders and inform therapeutic strategies for individuals with social cognition challenges.

How similar studies have performed: Previous research has shown promising results in understanding social gaze dynamics, but this specific approach using live interactions and non-human primates is relatively novel.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.