NIH-funded research R03 grant

Understanding how social factors affect metabolic syndrome and heart disease risk.

Official title: Metabolic Syndrome Severity in All of Us: Relationship with Social Determinants of Health and with Long-Term Risk for Cardiovascular Disease

Funded at University of Virginia · NIH-10925423 · Data updated 2026-11-12

This study is looking at how things like your background and living conditions affect the severity of metabolic syndrome, especially in diverse communities, to help create better health tools and personalized care for everyone.

More Cardiovascular Disease research and trials

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia
NIH-funded
Lab location1 site (Charlottesville, United States)
Project startSeptember 10, 2023
Project endAugust 31, 2025
Funding year2024
Award (this year)$154,751
NIH project number5R03HL172130-03
Project IDNIH-10925423 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals from minoritized racial and ethnic groups who may be at risk for metabolic syndrome and cardiovascular disease.

Less likely to help

Patients who do not belong to the targeted minoritized groups or those without metabolic syndrome may not benefit from this research.

What this research studies

This research investigates the relationship between metabolic syndrome severity and social determinants of health, particularly among minoritized groups. It aims to validate assessment tools that can help track metabolic syndrome, which is a cluster of risk factors for cardiovascular disease. By analyzing data from diverse populations, including African Americans and Asian Americans, the study seeks to develop personalized medicine approaches that consider unique health profiles and stress factors. Participants may contribute to a better understanding of how these factors influence long-term health outcomes.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cardiovascular disease in diverse populations.

How similar studies have gone: Previous research has shown success in using similar approaches to assess health disparities and metabolic syndrome in diverse populations.

Where this research is happening

  • University of Virginia
    Charlottesville, United States
    Active

Researchers

  • Principal investigator: Gurka, Matthew James — University of Virginia
  • Study coordinator: Gurka, Matthew James

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.