NIH-funded research R01 grant

Understanding how social factors affect fatty liver disease in different communities

Official title: Social determinants of fatty liver disease and its racial/ethnic disparities: The Multi-Ethnic Study of Atherosclerosis

Funded at Drexel University · NIH-11106004 · Data updated 2026-11-12

This project looks at how social and community factors contribute to fatty liver disease and why it affects some racial and ethnic groups more than others.

More Atherosclerosis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDrexel University
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startJuly 15, 2023
Project endMay 31, 2027
Funding year2025
Award (this year)$580,398
NIH project number5R01DK136171-03
Project IDNIH-11106004 on NIH RePORTER

Who could benefit from this research

Could help

This project uses existing data from a large, diverse group of people, so direct patient participation is not currently sought.

Less likely to help

Patients seeking immediate new treatments or direct clinical care will not find a direct benefit from this observational data analysis project.

What this research studies

We know that liver disease is a growing problem, especially fatty liver diseases like NAFLD and ALD, which affect many people worldwide. While individual habits like diet and alcohol use play a role, this project explores how broader social and community conditions also influence who gets fatty liver disease and why certain groups are more affected. We are using information from a large, ongoing health project called the Multi-Ethnic Study of Atherosclerosis (MESA) to understand these connections better. By looking at both individual and community factors, we hope to uncover new ways to address these health differences.

Why it matters

Potential benefit: If successful, this work could help us develop more effective public health strategies and interventions that consider social factors to reduce fatty liver disease and its unequal impact on different communities.

How similar studies have gone: While individual risk factors for fatty liver disease are well-known, research specifically on the role of social and community-level factors in its disparities is limited, making this a novel approach.

Where this research is happening

  • Drexel University
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Lazo Elizondo, Mariana — Drexel University
  • Study coordinator: Lazo Elizondo, Mariana

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.