NIH-funded research R01 grant

Understanding how social connections affect substance use and mental health

Official title: Characterizing the neural mechanisms of social connection

Funded at Rutgers the State Univ of Nj Newark · NIH-11012395 · Data updated 2026-11-12

This study looks at how feeling lonely affects mental health and substance use, and it’s for anyone dealing with substance dependence; it aims to understand how having strong social connections can help people cope better and make healthier choices.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers the State Univ of Nj Newark
NIH-funded
Lab location1 site (Newark, United States)
Project startApril 15, 2022
Project endJanuary 31, 2027
Funding year2025
Award (this year)$498,264
NIH project number5R01DA053311-04
Project IDNIH-11012395 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing substance dependence and social isolation, particularly those who may benefit from enhanced social support.

Less likely to help

Patients who are not struggling with substance use or who have strong social support networks may not receive direct benefits from this research.

What this research studies

This research investigates the impact of social isolation on mental health and substance use, focusing on how perceived social connections can mitigate negative outcomes. It aims to explore the neurobiological mechanisms that underlie the formation of social bonds and how these bonds can influence coping strategies for individuals struggling with substance dependence. By integrating social context into the understanding of substance abuse, the research seeks to identify ways to foster healthy social interactions that may reduce maladaptive behaviors.

Why it matters

Potential benefit: If successful, this research could lead to new interventions that help individuals form healthier social connections, potentially reducing substance use and improving mental health outcomes.

How similar studies have gone: Previous research has shown that social interactions can positively influence substance use behaviors, suggesting that this approach has potential for success.

Where this research is happening

  • Rutgers the State Univ of Nj Newark
    Newark, United States
    Active

Researchers

  • Principal investigator: Delgado, Mauricio R. — Rutgers the State Univ of Nj Newark
  • Study coordinator: Delgado, Mauricio R.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.