Understanding how smell memory is affected in older adults with Alzheimer's disease
Odor memory and functional neuroimaging in cognitively impaired older adults and Alzheimer's disease
['FUNDING_OTHER'] · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · NIH-10778609
This study is looking at how smell and memory are connected in older adults with Alzheimer's disease, and it involves smelling different scents while we check brain activity to learn more about how this condition affects memory.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10778609 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between odor memory and Alzheimer's disease by using advanced neuroimaging techniques. It aims to uncover the neural mechanisms that contribute to memory deficits related to smell in cognitively impaired older adults. The project involves training in neuroimaging methodologies and olfactory evaluations, which will help in identifying biomarkers associated with Alzheimer's disease. Participants may undergo assessments that include smelling various odors while their brain activity is monitored to better understand these connections.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing cognitive impairment or diagnosed with Alzheimer's disease.
Not a fit: Patients without cognitive impairment or those with other unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods for early detection of Alzheimer's disease based on odor memory.
How similar studies have performed: Previous research has shown promising results in using neuroimaging to study memory and Alzheimer's disease, indicating that this approach has potential for success.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOTTER, JEFFREY NICHOLAS — NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
- Study coordinator: MOTTER, JEFFREY NICHOLAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Neurodegenerative Disorders