Understanding how smell influences social behavior in autism

Dissecting the synaptic and circuit mechanisms underlying olfactory-driven social behavior

NIH-funded research Columbia University Health Sciences · NIH-10894945

This study is looking at how smells can influence social behaviors in people with autism, hoping to find new ways to help improve their social interactions and emotional responses.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10894945 on NIH RePORTER

What this research studies

This research investigates the neural mechanisms that connect olfactory (smell) cues to social behaviors, particularly in individuals with autism spectrum disorder (ASD). By examining the synaptic and circuit-level interactions in the brain, the study aims to uncover how these processes affect emotional responses and social interactions. The approach includes advanced techniques such as electrophysiology to measure brain activity and behavior assessments to evaluate social responses. Patients may benefit from insights that could lead to new therapeutic strategies for improving social functioning in autism.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder who may experience challenges in social interactions.

Not a fit: Patients without a diagnosis of autism or those who do not exhibit social behavior challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new interventions that enhance social behavior in individuals with autism.

How similar studies have performed: Previous research has shown promising results in understanding the link between sensory processing and social behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.