Understanding how small vesicles affect heart problems in diabetic patients
Critical Role of Small Extracellular Vesicles in Diabetic Coronary VascularDysfunction and Diabetic Ischemic Heart Failure efforts
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10823291
This study is looking at how tiny particles released from fat tissue might affect heart problems in people with type 2 diabetes, with the goal of finding ways to improve heart health and circulation for those living with this condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-10823291 on ClinicalTrials.gov |
What this research studies
This research investigates the role of small extracellular vesicles in the development of coronary vascular dysfunction and ischemic heart failure in patients with type 2 diabetes. It aims to identify the risk factors and mechanisms that contribute to these conditions, focusing on how adipose tissue communicates with the heart. By clarifying these interactions, the research seeks to develop effective interventions that could improve coronary circulation and reduce the severity of heart failure in diabetic patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 2 diabetes who are at risk for or experiencing ischemic heart failure.
Not a fit: Patients without diabetes or those with other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve heart health and reduce complications for patients with diabetes.
How similar studies have performed: Previous research has shown promise in understanding the role of adipose tissue in diabetes-related heart conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, YAJING — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: WANG, YAJING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.