Understanding how small molecules control the behavior and development of a tiny worm.
Administrative supplement to promote diversity in health-related research: Melisa Gonzalez
This study is looking at how tiny signals in a small worm help control its growth and behavior, and by understanding these signals better, we hope to find new ways to help people with similar metabolic and developmental issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11090703 on NIH RePORTER |
What this research studies
This research investigates the small-molecule signals that the nematode Caenorhabditis elegans uses to regulate its growth, metabolism, and behavior. By employing advanced techniques like CRISPR-Cas9, researchers aim to create specific mutations in the worm's genome to study how these changes affect the production of important signaling molecules. The findings could reveal how these signals influence various biological processes, potentially leading to insights applicable to other organisms. Patients may benefit from a deeper understanding of metabolic and developmental processes that could inform treatments for related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in the biological mechanisms of metabolism and development, particularly those with metabolic disorders.
Not a fit: Patients with conditions unrelated to metabolic signaling or those not interested in basic biological research may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of metabolic signaling, potentially leading to new therapeutic strategies for metabolic disorders.
How similar studies have performed: Other research has shown success in understanding metabolic signaling pathways in model organisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Butcher, Rebecca a — University of Florida
- Study coordinator: Butcher, Rebecca a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.