Understanding how small cell lung cancer changes and resists treatment
Modeling tumor heterogeneity and treatment resistance in small cell lung cancer
This study is looking at small cell lung cancer to find better ways to treat it by understanding how the cancer changes and resists treatment, using blood and tumor samples from patients to help improve future therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10928727 on NIH RePORTER |
What this research studies
This research focuses on small cell lung cancer (SCLC), a type of cancer known for its aggressive nature and quick development of resistance to treatments. The team at the University of Texas M.D. Anderson Cancer Center is working to identify new therapeutic targets and improve responses to immunotherapy by studying the genetic and molecular characteristics of the cancer. They are using innovative techniques to analyze blood and tumor samples from patients, which allows for a non-invasive approach to understanding how the disease evolves and resists treatment. By creating models that reflect patient-specific disease characteristics, the research aims to uncover the mechanisms behind treatment resistance and improve future therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with small cell lung cancer who are undergoing treatment or have relapsed after initial therapy.
Not a fit: Patients with other types of lung cancer or those who are not currently receiving treatment for small cell lung cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for small cell lung cancer, improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in using similar approaches to study cancer treatment resistance, indicating that this methodology could yield valuable insights.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Stewart, Catherine Allison — University of Tx Md Anderson Can Ctr
- Study coordinator: Stewart, Catherine Allison
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.