Understanding how small blood vessel disease affects brain function and dementia.
Cerebral Small Vessel Disease and Dementia: Defining Global Resilience and Disruption in Brain Networks
This study is looking at how problems with tiny blood vessels in the brain might be linked to dementia, especially Alzheimer's, to help us understand how they affect thinking and memory in older adults.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-11032093 on NIH RePORTER |
What this research studies
This research investigates the relationship between cerebral small vessel disease and dementia, particularly Alzheimer's disease and related dementias. It aims to uncover how small blood vessel issues contribute to cognitive decline and affect brain networks. By focusing on cerebral microbleeds, the study seeks to fill existing knowledge gaps regarding their impact on cognitive function in older adults. The research is conducted at Wake Forest University Health Sciences, a leader in geriatric research.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing cognitive decline or showing early signs of dementia.
Not a fit: Patients with dementia not related to small vessel disease or those with other unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of dementia, enhancing the quality of life for older adults.
How similar studies have performed: Previous research has shown promising results in understanding the effects of small vessel disease on cognitive function, suggesting this approach has potential for significant insights.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Bahrami, Mohsen — Wake Forest University Health Sciences
- Study coordinator: Bahrami, Mohsen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.